Research: Bioactive Molecules

The Bioactive Molecules (BAM) laboratory at the University of Texas at Austin is focused on engaging students in authentic research experiences in synthetic organic chemistry. Directed by Dr. Elizabeth Ilardi, BAM is an extension of the Martin Research Group, and assists in the investigation of the design and synthesis of small organic molecules that have the potential to bind tightly and selectively to biologically significant proteins. In this research, students are introduced to multidisciplinary research through active learning, written assignments and activities, and guided laboratory experimentation to foster digital literacy and technical competency relevant to the field of DRUG DISCOVERY.

Conceptual Background/ Prep


INTRO TO DRUG DISCOVERY AND DRUG DESIGN

Organic Nomenclature & Structures S

Naming Rules

Functional Groups & Pharmacaphores S

Functional Groups in OChem

Functional Group Interconversions

Pharmacaphores

Drug Discovery & How Drugs Work S

Drug Discovery & Research Overview

Rules to the Game (web)

Rules to the Game (ppt)

Intro Drug Discovery (Updated)

PROTEINS/RECEPTORS & LIGAND INTERACTIONS

Introduction to Proteins S

Amino Acids (Chart)

PyMOL Activity

Protein Data Bank (PDB)

RESEARCH DATABASES & SOFTWARE

Drawing Molecules using MarvinSketch

Protein Modeling using PyMOL

Downloads: BetaSheet.pdb Helix.pdb

BIOACTIVE MOLECULES LAB BACKGROUND

Intro Drug Discovery &

Bioactive Molecules Research Summary

Background Research Article

Resources